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... In 1995 Messing made her film debut, in the director Alfonso Arau's love story A Walk in the Clouds, in which she had a small role as the wife of a World War II veteran (Keanu Reeves). This exposure led the Fox network to make her the co-star of the television sitcom Ned and Stacey; the series, about a young man and a young woman who marry for reasons other than love after knowing each other for only a week, lasted for two seasons (1995-1997). Messing appeared as Jerry Seinfeld's date in two episodes of the hit television show Seinfeld: "The Wait Out" in 1996, and "The Yada Yada" in 1997. The actress turned down a starring role in another television sitcom to appear in Donald Margulies?s two-character play Collected Stories, which opened at the Manhattan Theater Club, an Off-Broadway venue, in 1997. Messing portrayed the prote'ge' and, ultimately, literary betrayer of a famous short-story writer (Maria Tucci).

In 1998 Messing had a lead role as the bioanthropologist Sloan Parker on ABC's dramatic science-fiction television series Prey. Meanwhile, Messing's agent had approached the actress with the pilot script for the television show Will & Grace, Messing was inclined to take some time off, but the pilot for Will & Grace intrigued her.

Messing was hand-picked by Woody Allen for a small role in his movie Celebrity (1998). In an interview later, Messing described the method Allen used to enable her to discover the essence of her character, one that resulted in nerve-racking uncertainty for the actress, who during her first four days on the set got no feedback from Allen. After he offered his first words of guidance, on the fifth day, Messing felt herself undergoing a transformation.

Messing's big-screen roles also include turns as a happily married but ill-fated wife in the supernatural thriller The Mothman Prophecies (2002), which also starred Richard Gere.

Messing met her future husband, Daniel Zelman, an actor and screenwriter, on their first day as graduate students at NYU. She and Zelman, who were married on September 3, 2000, live in Los Angeles. ~Answers.com.
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